Check out the companies making headlines before the opening bell : Metsera , Pfizer — The weight-loss drugmaker soared 60% after an announcement it would be bought by Pfizer for $4.9 billion in cash. The deal is expected to close in the fourth quarter. Pfizer shares ticked nearly 3% higher. Anywhere , Compass — Brokerage giant Compass plans to take over rival Anywhere, the parent of Century 21 and Coldwell Banker, for $1.6 billion in an all-stock transaction. The combined company is expected to have an enterprise value of approximately $10 billion, including the assumption of debt. Anywhere shares shot up more than 50%, while Compass shares dipped about 9%. Sarepta Therapeutics — The biotech company climbed 6% after an upgrade to outperform by BMO, which also called for the stock to more than double. “SRPT’s current valuation renders its risk/reward skewed to the upside,” the investment bank said. Crown Castle — The cell tower operator added 1.1% on the back of Wolfe Research’s upgrade to outperform from peer perform. Wolfe said the stock is trading at a good entry point. Kenvue — The Tylenol maker fell 5% after the Washington Post reported the Trump administration plans to announce Monday that use of the painkiller by pregnant women is linked to autism. Fox Corporation — President Donald Trump said in a Sunday interview that conservative media baron Rupert Murdoch and his son Lachlan, the chief executive of Fox Corp., are likely to be involved in the deal to save TikTok in the U.S . Fox Corp shares gained nearly 4% in premarket trading. Applied Materials — Shares gained more than 1% after a Morgan Stanley upgrade to overweight from equal weight. The investment bank noted that the chipmaker trades at an attractive valuation relative to peers. — CNBC’s Alex Harring, Fred Imbert and Michelle Fox contributed reporting.
https://www.cnbc.com/2025/09/22/stocks-making-the-biggest-premarket-moves-mtsr-comp-kvue-foxa.html
