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TUCSON, Ariz. — Nancy Guthrie’s family members have been cleared as suspects in the investigation into her disappearance, according to Pima County Sheriff Chris Nanos.
“To be clear…the Guthrie family – to include all siblings and spouses – has been cleared as possible suspects in this case,” Nanos said in a Monday afternoon statement. “The family has been nothing but cooperative and gracious and are victims in this case.
“To suggest otherwise is not only wrong, it is cruel,” he added. “The Guthrie family are victims plain and simple…please, I’m begging you the media to honor your profession and report with some sense of compassion and professionalism.”
Savannah Guthrie (C) and her siblings Annie (L) and Camron made an emotional plea on Instagram asking anyone with information about their mother Nancy Guthrie’s disappearance to come forward on February 4, 2025. (Credit: Instagram/@SavannahGuthrie/Today)
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Nanos also told Fox News on Friday that DNA evidence from the home did not match family members “or anyone in close contact to her.”
The announcement comes after intense online speculation that a family member might have been involved.
Monday marked the beginning of the third week of the investigation, which has yielded little in the way of answers about the family matriarch’s whereabouts.
However, there are five key pieces of evidence that investigators have discussed as Monday.
The first is a dramatic doorbell camera video released by the FBI showing a masked suspect approaching Guthrie’s front door in the dead of night. According to FBI analysts, the suspect is between 5 feet, 9 inches tall and 5 feet, 10 inches tall and has an average build. He was wearing a black Ozark Trail brand backpack, sold at Walmart.
The second is a DNA sample that came from an unknown individual inside Guthrie’s home.
Photos released on Feb. 10, 2025, show a “subject” on Nancy Guthrie’s property. (Provided by FBI)
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The FBI is checking the DNA against a glove recovered from inside a two-mile search radius around the house, and said it “appears to match the gloves of the subject in the surveillance video.” Federal law enforcement also said the glove contained DNA consistent with an “unknown male profile.”
The DNA profile is expected to be run through CODIS in the near future.
The third is blood that is a genetic match to Guthrie’s, which was found on her front porch. It remains unclear when the blood was spilled.
Authorities also know that Guthrie’s pacemaker lost connection to the phone application it was tethered to at 2:28 a.m. on Sunday, Feb. 1. They used a high-tech Bluetooth scanning device, placed in a low-flying helicopter, to try to detect the pacemaker. That was unsuccessful.
FBI investigators canvass the neighborhood around Annie Guthrie’s home in Tucson, Arizona, Tuesday, February 10, 2026. The investigations into the disappearance of her mother, Nancy Guthrie continues. (DWS for Fox News Digital)
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Nancy Guthrie disappearance timeline:
Jan. 31, 2026
• Between 9:30–9:45 p.m. – Family drops Nancy off at home
• 9:50 p.m. – Garage door closes (per authorities)
Feb. 1, 2026
• 1:47 a.m. – Doorbell camera disconnects
• 2:12 a.m. – Security camera detects motion
• 2:28 a.m. – Pacemaker disconnects from phone application
• 11:56 a.m. – Family checks on Nancy after she misses weekly church livestream gathering
• 12:03 p.m. — 911 called
• 12:15 p.m. — Sheriff’s deputies arrive at home
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